Zoster Vaccine Market

Zoster Vaccine Market Size By Product (SKYZoster, Zostavax, and Shingrix), and By Vaccine Type (Live Attenuated Vaccine and Recombinant Vaccine), Regions, Global Industry Analysis, Share, Growth, Trends, and Forecast 2024 to 2033

Base Year: 2023 Historical Data: 2020-22
  • Report ID: TBI-14423
  • Published Date: Jun, 2024
  • Pages: 238
  • Category: Healthcare
  • Format: PDF
Buy @ $4700.00 Request Sample PDF

The global zoster vaccine market was valued at USD 4.2 billion in 2023, growing at a CAGR of 8.1% from 2024 to 2033 and expected to reach USD 9.1 billion by 2033. The market is anticipated to rise due to improved healthcare policies in developed nations and the increasing risk of shingles, particularly in adults 60 years of age and above.

Market Introduction:

The varicella-zoster vaccine, often known as the shingles vaccine, is an essential prophylactic against herpes zoster, a disease caused by the reactivation of the varicella-zoster virus that also causes chickenpox. A weakened version of the virus is used in this vaccination to encourage the production of antibodies by the immune system that can lessen or even prevent the severity of shingles. Its principal use is preventing shingles in those 50 years of age and older, who are more susceptible to age-related immune decline. The vaccine also lessens the risk of shingles-related consequences like neurological problems and chronic pain. Currently, the two primary zoster vaccines on the market are Zostavax and Shingrix, while further research is looking towards even more potent vaccines with wider uses. To decrease the cases of shingles related diseases, it is very much necessary to reduce the doses of medicine required for protection. Furthermore, looking into combination vaccines for streamlined immunisation schedules can also help reduce the cases of shingles worldwide.

Zoster Vaccine Market Size

Get an overview of this study by requesting a free sample

Recent Development

In February 2023, a phase 1/2 investigation was initiated to learn more about the safety, tolerability, and immunogenicity of Pfizer Inc. and BioNTech SE's mRNA vaccine candidates against varicella-zoster virus (VZV), which causes shingles, a serious illness also known as herpes zoster or HZ.  

In February 2023, Jiangsu Recbio Technology Co., Ltd. concluded its initial round of subject enrollment for its adjuvanted recombinant shingles vaccine, REC610.

Market Dynamics:


Increasing disease prevalence- One of the key factors propelling the market is the increasing incidence of shingles worldwide. Preventive actions are necessary as the ageing population raises the incidence of shingles and its associated consequences.


Limited vaccine uptake- Even with strong advice, vaccination rates are still comparatively low in certain areas. Market expansion is hampered by misinformation, reluctance to get vaccinations, and side effect worries.


Increasing cases of herpes zoster- During the forecast period, vaccination uptake is anticipated to rise due to the rising number of herpes zoster cases reported globally. According to estimates, there are three to five cases of herpes zoster per 1,000 people annually, and the frequency rises with age. A study in Germany estimates that there are 5.79 incidences of zoster annually per 1,000 people. It is anticipated that the high risk of herpes zoster will lead to a rise in the use of shingles vaccinations.

Regional segmentation analysis:

The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America emerged as the largest global zoster vaccine market, with a 42.3% market revenue share in 2023.

The market for zoster vaccines has increased due to the rising incidence of chickenpox in North America. The varicella-zoster virus, which causes shingles and chickenpox, is the same infection. Despite being a common childhood infection, chickenpox can be caused by a virus that goes dormant in the body and reactivates later in life as shingles. The public health response to chickenpox epidemics may also include recommendations for the shingles vaccination, particularly for individuals who are more vulnerable because of age or underlying medical conditions.

North America Region Zoster Vaccine Market Share in 2023 - 42.3%



Check the geographical analysis of this market by requesting a free sample

Product Segment Analysis

The product segment is divided into SKYZoster, zostavax, and shingrix. The shingrix segment dominated the market, with a market share of around 42% in 2023.  The market for zoster vaccines is anticipated to be driven by the increasing adoption of the shingrix vaccination. Regarding avoiding zoster, shingrix is a highly efficient vaccination that has been found to offer longer-lasting protection than other vaccines on the market.

Vaccine Type Segment Analysis

The vaccine type segment is divided into live attenuated vaccine and recombinant vaccine. The recombinant vaccine segment dominated the market, with a market share of around 58% in 2023. Genetic engineering methods are used to create recombinant vaccines, which enable more accurate targeting of the virus or organism being treated. New vaccinations, such as the shingles vaccine shingrix, have been created using this technology. Recombinant vaccines are becoming more popular than conventional ones since they are safer, more effective, and easier to produce. They are, therefore, growing in popularity among patients and healthcare professionals. Purified antigenic pathogen components—that is, required to trigger a defensive immune response—are included in this vaccine.

Some of the Key Market Players:
  • Merck & Co., Inc.
  • Changchun BCHT Biotechnology Co
  • Vaccitech
  • Pfizer Inc
  • Jiangsu Recbio Technology Co., Ltd
  • GSK plc
  • SK chemicals
  • Geneone Life Science
  • CanSinoBIO
  • Curevo Inc

Report Description:

Attribute Description
Market Size Revenue (USD Billion)
Market size value in 2023 USD 4.2 Billion
Market size value in 2033 USD 9.1 Billion
CAGR (2024 to 2033) 8.1%
Historical data 2020-2022
Base Year 2023
Forecast 2024-2033
Region The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East & Africa. Furthermore, the regions are further analyzed at the country level.
Segments Product, Vaccine Type

Frequesntly Asked Questions

As per The Brainy Insights, the size of the zoster vaccine market was valued at USD 4.2 billion in 2023 to USD 9.1 billion by 2033.

The global zoster vaccine market is growing at a CAGR of 8.1% during the forecast period 2024-2033.

North America emerged as the largest zoster vaccine market.

Key players in the zoster vaccine market are Merck & Co., Inc., Changchun BCHT Biotechnology Co, Vaccitech, Pfizer Inc, Jiangsu Recbio Technology Co., Ltd, GSK plc, SK chemicals, Geneone Life Science, CanSinoBIO, and Curevo Inc.

Request Table of Content


This study forecasts global, regional, and country revenue from 2020 to 2033. The Brainy Insights has segmented the global zoster vaccine market based on the below-mentioned segments:

Global Zoster Vaccine Market By Product:

  • SKYZoster
  • Zostavax
  • Shingrix

Global Zoster Vaccine Market By Vaccine Type:

  • Live Attenuated Vaccine
  • Recombinant Vaccine

Global Zoster Vaccine Market By Region:                                    

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
  • Asia-Pacific
    • Japan
    • China
    • India
  • South America
    • Brazil
  • Middle East and Africa  
    • UAE
    • South Africa


Research has its special purpose to undertake marketing efficiently. In this competitive scenario, businesses need information across all industry verticals; the information about customer wants, market demand, competition, industry trends, distribution channels etc. This information needs to be updated regularly because businesses operate in a dynamic environment. Our organization, The Brainy Insights incorporates scientific and systematic research procedures in order to get proper market insights and industry analysis for overall business success. The analysis consists of studying the market from a miniscule level wherein we implement statistical tools which helps us in examining the data with accuracy and precision. 

Our research reports feature both; quantitative and qualitative aspects for any market. Qualitative information for any market research process are fundamental because they reveal the customer needs and wants, usage and consumption for any product/service related to a specific industry. This in turn aids the marketers/investors in knowing certain perceptions of the customers. Qualitative research can enlighten about the different product concepts and designs along with unique service offering that in turn, helps define marketing problems and generate opportunities. On the other hand, quantitative research engages with the data collection process through interviews, e-mail interactions, surveys and pilot studies. Quantitative aspects for the market research are useful to validate the hypotheses generated during qualitative research method, explore empirical patterns in the data with the help of statistical tools, and finally make the market estimations.

The Brainy Insights offers comprehensive research and analysis, based on a wide assortment of factual insights gained through interviews with CXOs and global experts and secondary data from reliable sources. Our analysts and industry specialist assume vital roles in building up statistical tools and analysis models, which are used to analyse the data and arrive at accurate insights with exceedingly informative research discoveries. The data provided by our organization have proven precious to a diverse range of companies, facilitating them to address issues such as determining which products/services are the most appealing, whether or not customers use the product in the manner anticipated, the purchasing intentions of the market and many others.

Our research methodology encompasses an idyllic combination of primary and secondary initiatives. Key phases involved in this process are listed below:


Data Procurement:

The phase involves the gathering and collecting of market data and its related information with the help of different sources & research procedures.

The data procurement stage involves in data gathering and collecting through various data sources.

This stage involves in extensive research. These data sources includes:

Purchased Database: Purchased databases play a crucial role in estimating the market sizes irrespective of the domain. Our purchased database includes:

  • The organizational databases such as D&B Hoovers, and Bloomberg that helps us to identify the competitive scenario of the key market players/organizations along with the financial information.
  • Industry/Market databases such as Statista, and Factiva provides market/industry insights and deduce certain formulations. 
  • We also have contractual agreements with various reputed data providers and third party vendors who provide information which are not limited to:
    • Import & Export Data
    • Business Trade Information
    • Usage rates of a particular product/service on certain demographics mainly focusing on the unmet prerequisites

Primary Research: The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. Primary research mainly involves in telephonic interviews, E-mail interactions and face-to-face interviews with the raw material providers, manufacturers/producers, distributors, & independent consultants. The interviews that we conduct provides valuable data on market size and industry growth trends prevailing in the market. Our organization also conducts surveys with the various industry experts in order to gain overall insights of the industry/market. For instance, in healthcare industry we conduct surveys with the pharmacists, doctors, surgeons and nurses in order to gain insights and key information of a medical product/device/equipment which the customers are going to usage. Surveys are conducted in the form of questionnaire designed by our own analyst team. Surveys plays an important role in primary research because surveys helps us to identify the key target audiences of the market. Additionally, surveys helps to identify the key target audience engaged with the market. Our survey team conducts the survey by targeting the key audience, thus gaining insights from them. Based on the perspectives of the customers, this information is utilized to formulate market strategies. Moreover, market surveys helps us to understand the current competitive situation of the industry. To be precise, our survey process typically involve with the 360 analysis of the market. This analytical process begins by identifying the prospective customers for a product or service related to the market/industry to obtain data on how a product/service could fit into customers’ lives.

Secondary Research: The secondary data sources includes information published by the on-profit organizations such as World bank, WHO, company fillings, investor presentations, annual reports, national government documents, statistical databases, blogs, articles, white papers and others. From the annual report, we analyse a company’s revenue to understand the key segment and market share of that organization in a particular region. We analyse the company websites and adopt the product mapping technique which is important for deriving the segment revenue. In the product mapping method, we select and categorize the products offered by the companies catering to domain specific market, deduce the product revenue for each of the companies so as to get overall estimation of the market size. We also source data and analyses trends based on information received from supply side and demand side intermediaries in the value chain. The supply side denotes the data gathered from supplier, distributor, wholesaler and the demand side illustrates the data gathered from the end customers for respective market domain.

The supply side for a domain specific market is analysed by:

  • Estimating and projecting penetration rates through analysing product attributes, availability of internal and external substitutes, followed by pricing analysis of the product.
  • Experiential assessment of year-on-year sales of the product by conducting interviews.

The demand side for the market is estimated through:

  • Evaluating the penetration level and usage rates of the product.
  • Referring to the historical data to determine the growth rate and evaluate the industry trends

In-house Library: Apart from these third-party sources, we have our in-house library of qualitative and quantitative information. Our in-house database includes market data for various industry and domains. These data are updated on regular basis as per the changing market scenario. Our library includes, historic databases, internal audit reports and archives.

Sometimes there are instances where there is no metadata or raw data available for any domain specific market. For those cases, we use our expertise to forecast and estimate the market size in order to generate comprehensive data sets. Our analyst team adopt a robust research technique in order to produce the estimates:

  • Applying demographic along with psychographic segmentation for market evaluation
  • Determining the Micro and Macro-economic indicators for each region 
  • Examining the industry indicators prevailing in the market. 

Data Synthesis: This stage involves the analysis & mapping of all the information obtained from the previous step. It also involves in scrutinizing the data for any discrepancy observed while data gathering related to the market. The data is collected with consideration to the heterogeneity of sources. Robust scientific techniques are in place for synthesizing disparate data sets and provide the essential contextual information that can orient market strategies. The Brainy Insights has extensive experience in data synthesis where the data passes through various stages:

  • Data Screening: Data screening is the process of scrutinising data/information collected from primary research for errors and amending those collected data before data integration method. The screening involves in examining raw data, identifying errors and dealing with missing data. The purpose of the data screening is to ensure data is correctly entered or not. The Brainy Insights employs objective and systematic data screening grades involving repeated cycles of quality checks, screening and suspect analysis.
  • Data Integration: Integrating multiple data streams is necessary to produce research studies that provide in-depth picture to the clients. These data streams come from multiple research studies and our in house database. After screening of the data, our analysts conduct creative integration of data sets, optimizing connections between integrated surveys and syndicated data sources. There are mainly 2 research approaches that we follow in order to integrate our data; top down approach and bottom up approach.

Market Deduction & Formulation: The final stage comprises of assigning data points at appropriate market spaces so as to deduce feasible conclusions. Analyst perspective & subject matter expert based holistic form of market sizing coupled with industry analysis also plays a crucial role in this stage.

This stage involves in finalization of the market size and numbers that we have collected from data integration step. With data interpolation, it is made sure that there is no gap in the market data. Successful trend analysis is done by our analysts using extrapolation techniques, which provide the best possible forecasts for the market.

Data Validation & Market Feedback: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helps us finalize data-points to be used for final calculations.

The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. The data validation interview and discussion panels are typically composed of the most experienced industry members. The participants include, however, are not limited to:

  • CXOs and VPs of leading companies’ specific to sector
  • Purchasing managers, technical personnel, end-users
  • Key opinion leaders such as investment bankers, and industry consultants

Moreover, we always validate our data and findings through primary respondents from all the major regions we are working on.

Some Facts About The Brainy Insights


Free Customization


Fortune 500 Clients


Free Yearly Update On Purchase Of Multi/Corporate License


Companies Served Till Date