Global protein expression market is projected to reach USD 4.21 billion by 2028, at a CAGR of 10.21% from 2021 to 2028. Increasing demand for a novel biologic drug to treat serious chronic diseases, including anemia, cancer, and multiple sclerosis is a significant contributing factor to market growth.
Protein expression refers to the way proteins in living organisms are synthesized, modified, and regulated. Protein expression in protein research can also refer to the usage of the laboratory techniques necessary for the production of proteins. In addition, protein expression has become a significant laboratory technology in molecular biology and protein research, biochemistry, as well as many fields of scientific research involving functional proteins for their research. Expressed protein products which are functional and exhibit similar characteristics to their native counterparts are useful for further study such as determining the three-dimensional protein structure, as chemical tools, or as new forms of drugs, among others. Moreover, protein expression can provide enzymes or substrates necessary for further study. Proteins are synthesized and regulated according to cell functional need. The protein blueprints are stored in DNA and decoded for the production of messenger RNA (mRNA) through highly regulated transcription processes. The mRNA-coded message is then converted into a protein. Transcription is the transfer of DNA information to mRNA, and translation is the synthesis of protein based on a sequence specified by mRNA.
The processing of proteins plays a significant role in numerous applications including the production of therapeutic proteins, the production of biologics and research application. Manufacturers use numerous expression systems such as mammalian cells, prokaryotic, insect cells, and yeast systems for genomics research, proteomics research, development, and manufacturing of biologics products. Hence, the demand for these products is anticipated to increase over the forecast period.
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The main factor driving demand growth is projected to be the growing incidence of many chronic diseases like arthritis, cancer, diabetes, asthma and infectious diseases. Therefore, there is a rise in demand for advanced biologics like therapeutic protein to cure chronic diseases like these. The manufacturers use such products extensively for the development and production of biologics. Thus, rising demand for biologics is anticipated to fuel the adoption of protein expression products.
Aspects such as rising market consolidations impacting new entrants, as well as the high cost of protein expression reagents and instruments impede the protein expression market growth.
Growing pharmaceutical sector and rising proteomics are opportunities fueling growth in the global protein expression market. The declining R&D costs of production and the decrease in sales due to the forthcoming patent cliff, the rising research in the pharmaceutical industry are likely to be the key factors that will boost global protein expression market growth.
Strict government regulations for biologics development and production could hamper the market growth. Before regulatory approval, the new biologics undergo rigorous clinical and preclinical trials. The commercialization of biologics, including hormones, insulin, therapeutic antibodies, vaccines, relies on the successful completion of clinical trials.
The global protein expression market has been segmented based on type, products, application, end-user and regions.
The regions evaluated for the protein expression market include Europe, North America, Middle East and Africa, South America and Asia Pacific. The North America region emerged as the largest market for protein expression, with a 38.4% share of market revenue in 2020.
North America Protein Expression Market Share in 2020 - 38.4%
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In 2017,Thermo Fisher Scientific Inc. introduced Thermo Scientific Krios G3i, the product is made to provide the revolutionary enhancements required for the steady adoption of cryo-EM (a form of electron microscopy transmission). The company has introduced Thermo Scientific Glacios, which produces high-performance Cryo-EM accessible to a wide range of pharmaceutical scientistsfor pharmaceutical drug development and discovery.
As per The Brainy Insights, the size of the protein expression market was valued at USD 1.91 billion in 2020 and is anticipated to reach USD 4.21 billion by 2028.
Global protein expression market is growing at a CAGR of 11.21% during the forecast period 2021-2028.
The global protein expression market has been segmented based on type, products, application, end-user and regions. The prokaryotic expression systems segment held the largest market share in 2020.
The North America region emerged as the largest market for the protein expression.
Rising prevalence of many chronic diseases is the key driving factor for the protein expression market.
High cost could hamper the market growth.
Increasing research in the pharmaceutical sector will provide huge opportunities to the market.
Key players are Agilent Technologies Inc., Bio-Rad Laboratories, Inc., Genscript Biotech Corporation, MerckKGaA, New England Biolabs, Promega Corporation
1. Introduction
1.1. Objectives of the Study
1.2. Market Definition
1.3. Research Scope
1.4. Currency
1.5. Key Target Audience
2. Research Methodology and Assumptions
3. Executive Summary
4. Premium Insights
4.1. Porter’s Five Forces Analysis
4.2. Value Chain Analysis
4.3. Top Investment Pockets
4.3.1. Market Attractiveness Analysis By System Type
4.3.2. Market Attractiveness Analysis By Product and Service
4.3.3. Market Attractiveness Analysis By Application
4.3.4. Market Attractiveness Analysis End-user
4.3.5. Market Attractiveness Analysis By Region
4.4. Industry Trends
5. Market Dynamics
5.1. Market Evaluation
5.2. Drivers
5.2.1. Rising Prevalence of Many Chronic Diseases
5.3. Restrains
5.3.1. High Cost
5.4. Opportunities
5.4.1. Increasing Research in the Pharmaceutical Sector
5.5. Challenges
5.5.1. Strict Government Regulations
6. Global Protein Expression Market Analysis and Forecast, By System Type
6.1. Segment Overview
6.2. Prokaryotic Expression Systems
6.3. Insect Cell Expression Systems
6.4. Mammalian Cell Expression Systems
6.5. Yeast Expression Systems
6.6. Algal-Based Expression Systems
6.7. Cell-free Expression Systems
7. Global Protein Expression Market Analysis and Forecast, By Product and Service
7.1. Segment Overview
7.2. Reagents
7.3. Competent Cells
7.4. Expression Vectors
7.5. Instruments
7.6. Services
8. Global Protein Expression Market Analysis and Forecast, By Application
8.1. Segment Overview
8.2. Therapeutic Applications
8.3. Industrial Applications
8.4. Research Applications
9. Global Protein Expression Market Analysis and Forecast, End-user
9.1. Segment Overview
9.2. Academic Research Institutes
9.3. Pharmaceutical and Biotechnology Companies
9.4. Contract Research Organizations (CROS)
9.5. Other End Users
10. Global Protein Expression Market Analysis and Forecast, By Regional Analysis
10.1. Segment Overview
10.2. North America
10.2.1. U.S.
10.2.2. Canada
10.2.3. Mexico
10.3. Europe
10.3.1. Germany
10.3.2. France
10.3.3. U.K.
10.3.4. Italy
10.3.5. Spain
10.4. Asia-Pacific
10.4.1. Japan
10.4.2. China
10.4.3. India
10.5. South America
10.5.1. Brazil
10.6. Middle East and Africa
10.6.1. UAE
10.6.2. South Africa
11. Global Protein Expression Market-Competitive Landscape
11.1. Overview
11.2. Market Share of Key Players in GlobalProtein Expression Market
11.2.1. Global Company Market Share
11.2.2. North America Company Market Share
11.2.3. Europe Company Market Share
11.2.4. APAC Company Market Share
11.3. Competitive Situations and Trends
11.3.1. Product Launches and Developments
11.3.2. Partnerships, Collaborations, and Agreements
11.3.3. Mergers & Acquisitions
11.3.4. Expansions
12. Company Profiles
12.1. Agilent Technologies Inc.
12.1.1. Business Overview
12.1.2. Company Snapshot
12.1.3. Company Market Share Analysis
12.1.4. Company Product Portfolio
12.1.5. Recent Developments
12.1.6. SWOT Analysis
12.2. Bio-Rad Laboratories, Inc.
12.2.1. Business Overview
12.2.2. Company Snapshot
12.2.3. Company Market Share Analysis
12.2.4. Company Product Portfolio
12.2.5. Recent Developments
12.2.6. SWOT Analysis
12.3. Genscript Biotech Corporation
12.3.1. Business Overview
12.3.2. Company Snapshot
12.3.3. Company Market Share Analysis
12.3.4. Company Product Portfolio
12.3.5. Recent Developments
12.3.6. SWOT Analysis
12.4. Merck KGaA
12.4.1. Business Overview
12.4.2. Company Snapshot
12.4.3. Company Market Share Analysis
12.4.4. Company Product Portfolio
12.4.5. Recent Developments
12.4.6. SWOT Analysis
12.5. New England Biolabs
12.5.1. Business Overview
12.5.2. Company Snapshot
12.5.3. Company Market Share Analysis
12.5.4. Company Product Portfolio
12.5.5. Recent Developments
12.5.6. SWOT Analysis
12.6. Promega Corporation
12.6.1. Business Overview
12.6.2. Company Snapshot
12.6.3. Company Market Share Analysis
12.6.4. Company Product Portfolio
12.6.5. Recent Developments
12.6.6. SWOT Analysis
12.7. Qiagen
12.7.1. Business Overview
12.7.2. Company Snapshot
12.7.3. Company Market Share Analysis
12.7.4. Company Product Portfolio
12.7.5. Recent Developments
12.7.6. SWOT Analysis
12.8. Takara Bio Inc.
12.8.1. Business Overview
12.8.2. Company Snapshot
12.8.3. Company Market Share Analysis
12.8.4. Company Product Portfolio
12.8.5. Recent Developments
12.8.6. SWOT Analysis
12.9. Thermo Fisher Scientific Inc.
12.9.1. Business Overview
12.9.2. Company Snapshot
12.9.3. Company Market Share Analysis
12.9.4. Company Product Portfolio
12.9.5. Recent Developments
12.9.6. SWOT Analysis
List of Table
1.Global Protein Expression Market, By System Type , 2018–2028 (USD Billion)
2.Global Prokaryotic Expression Systems, Protein Expression Market, By Region, 2018–2028 (USD Billion)
3.Global Insect Cell Expression Systems, Protein Expression Market, By Region, 2018–2028 (USD Billion)
4.Global Mammalian Cell Expression Systems, Protein Expression Market, By Region, 2018–2028 (USD Billion)
5.Global Yeast Expression Systems, Protein Expression Market, By Region, 2018–2028 (USD Billion)
6.Global Algal-Based Expression Systems, Protein Expression Market, By Region, 2018–2028 (USD Billion)
7.Global Cell-Free Expression Systems, Protein Expression Market, By Region, 2018–2028 (USD Billion)
8.Global Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
9.Global Reagents Protein Expression Market, By Region, 2018–2028 (USD Billion)
10.Global Competent Cells Protein Expression Market, By Region, 2018–2028 (USD Billion)
11.Global Expression Vectors Protein Expression Market, By Region, 2018–2028 (USD Billion)
12.Global Instruments Protein Expression Market, By Region, 2018–2028 (USD Billion)
13.Global Services Protein Expression Market, By Region, 2018–2028 (USD Billion)
14.Global Protein Expression Market, By Application, 2018–2028 (USD Billion)
15.Global Therapeutic Applications Protein Expression Market, By Region, 2018–2028 (USD Billion)
16.Global Industrial Applications Protein Expression Market, By Region, 2018–2028 (USD Billion)
17.Global Research Applications Protein Expression Market, By Region, 2018–2028 (USD Billion)
18.Global Protein Expression Market, End-user, 2018–2028 (USD Billion)
19.Global Academic Research Institutes Protein Expression Market, By Region, 2018–2028 (USD Billion)
20.Global Pharmaceutical and Biotechnology Companies Protein Expression Market, By Region, 2018–2028 (USD Billion)
21.Global Contract Research Organizations (CROs)Protein Expression Market, By Region, 2018–2028 (USD Billion)
22.Global Other End Users Protein Expression Market, By Region, 2018–2028 (USD Billion)
23.Global Protein Expression Market, By Region, 2018–2028 (USD Billion)
24.Global Protein Expression Market, By North America, 2018–2028 (USD Billion)
25.North America Protein Expression Market, By System Type , 2018–2028 (USD Billion)
26.North America Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
27.North America Protein Expression Market, By Application, 2018–2028 (USD Billion)
28.North America Protein Expression Market, End-user, 2018–2028 (USD Billion)
29.U.S. Protein Expression Market, By System Type , 2018–2028 (USD Billion)
30.U.S. Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
31.U.S. Protein Expression Market, By Application, 2018–2028 (USD Billion)
32.U.S. Protein Expression Market, End-user, 2018–2028 (USD Billion)
33.Canada Protein Expression Market, By System Type , 2018–2028 (USD Billion)
34.Canada Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
35.Canada Protein Expression Market, By Application, 2018–2028 (USD Billion)
36.Canada Protein Expression Market, End-user, 2018–2028 (USD Billion)
37.Mexico Protein Expression Market, By System Type , 2018–2028 (USD Billion)
38.Mexico Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
39.Mexico Protein Expression Market, By Application, 2018–2028 (USD Billion)
40.Mexico Protein Expression Market, End-user, 2018–2028 (USD Billion)
41.Europe Protein Expression Market, By System Type , 2018–2028 (USD Billion)
42.Europe Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
43.Europe Protein Expression Market, By Application, 2018–2028 (USD Billion)
44.Europe Protein Expression Market, End-user, 2018–2028 (USD Billion)
45.Germany Protein Expression Market, By System Type , 2018–2028 (USD Billion)
46.Germany Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
47.Germany Protein Expression Market, By Application, 2018–2028 (USD Billion)
48.Germany Protein Expression Market, End-user, 2018–2028 (USD Billion)
49.France Protein Expression Market, By System Type , 2018–2028 (USD Billion)
50.France Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
51.France Protein Expression Market, By Application, 2018–2028 (USD Billion)
52.France Protein Expression Market, End-user, 2018–2028 (USD Billion)
53.U.K. Protein Expression Market, By System Type , 2018–2028 (USD Billion)
54.U.K. Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
55.U.K. Protein Expression Market, By Application, 2018–2028 (USD Billion)
56.U.K. Protein Expression Market, End-user, 2018–2028 (USD Billion)
57.Italy Protein Expression Market, By System Type , 2018–2028 (USD Billion)
58.Italy Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
59.Italy Protein Expression Market, By Application, 2018–2028 (USD Billion)
60.Italy Protein Expression Market, End-user, 2018–2028 (USD Billion)
61.Spain Protein Expression Market, By System Type , 2018–2028 (USD Billion)
62.Spain Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
63.Spain Protein Expression Market, By Application, 2018–2028 (USD Billion)
64.Spain Protein Expression Market, End-user, 2018–2028 (USD Billion)
65.Asia Pacific Protein Expression Market, By System Type , 2018–2028 (USD Billion)
66.Asia Pacific Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
67.Asia Pacific Protein Expression Market, By Application, 2018–2028 (USD Billion)
68.Asia Pacific Protein Expression Market, End-user, 2018–2028 (USD Billion)
69.Japan Protein Expression Market, By System Type , 2018–2028 (USD Billion)
70.Japan Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
71.Japan Protein Expression Market, By Application, 2018–2028 (USD Billion)
72.Japan Protein Expression Market, End-user, 2018–2028 (USD Billion)
73.China Protein Expression Market, By System Type , 2018–2028 (USD Billion)
74.China Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
75.China Protein Expression Market, By Application, 2018–2028 (USD Billion)
76.China Protein Expression Market, End-user, 2018–2028 (USD Billion)
77.India Protein Expression Market, By System Type , 2018–2028 (USD Billion)
78.India Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
79.India Protein Expression Market, By Application, 2018–2028 (USD Billion)
80.India Protein Expression Market, End-user, 2018–2028 (USD Billion)
81.South America Protein Expression Market, By System Type , 2018–2028 (USD Billion)
82.South America Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
83.South America Protein Expression Market, By Application, 2018–2028 (USD Billion)
84.South America Protein Expression Market, End-user, 2018–2028 (USD Billion)
85.Brazil Protein Expression Market, By System Type , 2018–2028 (USD Billion)
86.Brazil Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
87.Brazil Protein Expression Market, By Application, 2018–2028 (USD Billion)
88.Brazil Protein Expression Market, End-user, 2018–2028 (USD Billion)
89.Middle East and Africa Protein Expression Market, By System Type , 2018–2028 (USD Billion)
90.Middle East and Africa Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
91.Middle East and Africa Protein Expression Market, By Application, 2018–2028 (USD Billion)
92.Middle East and Africa Protein Expression Market, End-user, 2018–2028 (USD Billion)
93.UAE Protein Expression Market, By System Type , 2018–2028 (USD Billion)
94.UAE Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
95.UAE Protein Expression Market, By Application, 2018–2028 (USD Billion)
96.UAE Protein Expression Market, End-user, 2018–2028 (USD Billion)
97.South Africa Protein Expression Market, By System Type , 2018–2028 (USD Billion)
98.South Africa Protein Expression Market, By Product and Service, 2018–2028 (USD Billion)
99.South Africa Protein Expression Market, By Application, 2018–2028 (USD Billion)
100.South Africa Protein Expression Market, End-user, 2018–2028 (USD Billion)
List of Figures
1.Global Protein Expression Market Segmentation
2.Protein Expression Market: Research Methodology
3.Market Size Estimation Methodology: Bottom-Up Approach
4.Market Size Estimation Methodology: Top-Down Approach
5.Data Triangulation
6.Porter’s Five Forces Analysis
7.Value Chain Analysis
8.Global Protein Expression Market Attractiveness Analysis By System Type
9.Global Protein Expression Market Attractiveness Analysis By Product and Service
10.Global Protein Expression Market Attractiveness Analysis By Application
11.Global Protein Expression Market Attractiveness Analysis End-user
12.Global Protein Expression Market Attractiveness Analysis By Region
13.Global Protein Expression Market: Dynamics
14.Global Protein Expression Market Share By System Type (2021 & 2028)
15.Global Protein Expression Market Share By Product and Service(2021 & 2028)
16.Global Protein Expression Market Share By Application(2021 & 2028)
17.Global Protein Expression Market Share End-user(2021 & 2028)
18.Global Protein Expression Market Share by Regions (2021 & 2028)
19.Global Protein Expression Market Share by Company (2020)
This study forecasts revenue growth at global, regional, and country levels from 2018 to 2028. The Brainy Insights has segmented the global protein expression market on the basis of below mentioned segments:
Global Protein Expression Market by System Type:
Global Protein Expression Market by Product and Service:
Global Protein Expression Market by Application:
Global Protein Expression Market by End-User:
Global Protein expression Market by Region:
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