Esomeprazole Market

Esomeprazole Market Sizes by Product Type (Tablets, Capsules and Others), By Application (Gastroesophageal Reflux Disease, Duodenal Ulcers and Others), Regions, Global Industry Analysis, Share, Growth, Trends, and Forecast 2024 to 2033

Base Year: 2023 Historical Data: 2020-22
  • Report ID: TBI-14085
  • Published Date: Feb, 2024
  • Pages: 237
  • Category: Healthcare
  • Format: PDF
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The global Esomeprazole market was valued at USD 1.91 billion in 2023 and is anticipated to grow at a CAGR of 5.35% from 2024 to 2033. Nexium is the brand name for esomeprazole, a compound that shares an isomer with omeprazole and comes as magnesium salt. It is a remedy for gastroesophageal reflux disease and peptic ulcers. It reduces stomach acid by treating esophagitis and Zollinger-Ellison syndrome through oral administration or direct vein injection. Although using it can cause some common side effects like headaches or constipation, abdominal pain, and dry mouth, some include angioedema, pneumonia & Clostridium infection impacts, which are observed less frequently. Esomeprazole has no side effects for pregnant women and nursing mothers who use it after delivery because its mechanism blocks H+/K+-ATPase cells inside their stomach, leading towards relief from symptoms associated mainly with disorders related to the digestive system. This effect helps alleviate symptoms related to GERD while providing overall benefits for patients experiencing esophagitis and other medical disorders linked directly to excess gastric acid within their digestive tracts.

Market Introduction:

Esomeprazole is a pharmaceutical drug which effectively treats diseases associated with excessive stomach acid and gastro disorders. The drug's efficacy lies in inhibiting the gastric parietal cells' proton pumps, reducing gastric acid secretion into the stomach. This pharmaceutical compound marks significant progress in managing disorders related to acidity by providing effectiveness much better than the other drug alternatives. Esomeprazole is predominantly used to treat gastroesophageal reflux disease (GERD), which occurs when stomach acid flows back into the esophagus. The gastroesophageal reflux disease (GERD) symptoms include chest pain, regurgitation and heartburn. Esomeprazole efficiently reduces acidity levels and relieves these symptoms by blocking the final stage of gastric acid production. Additionally, Esomeprazole has extensive application in treating both duodenal and gastric ulcers, as it facilitates recovery from existing lesions while reducing gastrin secretion to prevent new ulcer development. Such a two-pronged approach is vital for alleviating symptoms among afflicted individuals with peptic ulcers and inhibiting future incidents within the gastrointestinal tract.

Esomeprazole Market Size

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Recent Development
  • In October 2022: A clinical trial comparing the safety and effectiveness of tegoprazan against esomeprazole-containing bismuth triple treatment in Chinese patients infected with Helicobacter pylori was sponsored by Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.
  • In July 2022: To find out how the proton pump inhibitor esomeprazole affects the pharmacokinetics of BI 1819479 in plasma, Boehringer Ingelheim sponsored a clinical trial titled "A Study in Healthy Men to Test How Esomeprazole Influences the Amount of BI 1819479 in the Blood."

Market Dynamics:


Escalating Incidences of Gastroesophageal Reflux Disease (GERD) - The expansion of the global market can be attributed, to a great extent, to the escalating occurrences of gastroesophageal reflux disease (GERD) worldwide. Gastroesophageal reflux disease (GERD) is a persistent disease characterized by indications such as regurgitation and heartburn due to stomach acid going back into the esophagus. Unhealthy eating patterns, passive lifestyles, and obesity are rising exponentially, causing more people to have GERD, leading to elevated frequency rates of this condition, which has consequently stimulated the demand for robust anti-acid medicines like Esomeprazole. Esomeprazole is driven by significant market demand from gastric and duodenal peptic ulcers. Largely resulting from factors like prolonged use of NSAIDs, excessive alcohol consumption or infection with Helicobacter pylori bacteria, these ailments have become a global burden that requires medications for symptom relief as well as the promotion of tissue healing as such Esomeprazole has emerged as an invaluable therapeutic option in this regard.


Stringent Regulatory Scenario – The global Esomeprazole market faces a significant challenge in the form of complex regulations and rigorous approval procedures. Acquiring regulatory clearance for novel formulations or indications necessitates a substantial investment of time and effort. Global authorities impose stringent standards about safety and effectiveness, which are crucial for entry into the marketplace. Lags in this process can impede product releases, leading to constrained market penetration, thereby restricting growth prospects for Esomeprazole products. The Esomeprazole market faces a challenge due to the constant evolution of clinical evidence and treatment guidelines. Healthcare providers may reconsider their prescribing practices as new research emerges or updates are made to recommendations, leading to changes in the utilization of this drug. This aspect necessitates pharmaceutical companies adapting marketing strategies and educational initiatives depending on alterations in therapy duration, indications or potential associated risks.  


Growing Elderly Population - The growth of the Esomeprazole market is fueled by heightened recognition and detection of acid-related ailments. As medical facilities worldwide continue to advance, more individuals are accessing healthcare for gastrointestinal issues. Consequently, there has been a significant uptick in prescribing medications that suppress acid levels - with Esomeprazole being a highly favored option due to its effectiveness and low-risk profile. The ageing population strongly influences the Esomeprazole market, representing a significant demographic contributor to its growth. With higher vulnerability to gastrointestinal disorders such as GERD and peptic ulcers, elderly individuals experience an increased incidence of acid-related conditions due to changes in their digestive system. As this global population segment continues to increase, demand for medications like Esomeprazole is anticipated to rise, leading towards further expansion within the market.  

Regional segmentation analysis:

The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America region emerged as the most prominent global Esomeprazole market, with a 39.0% market revenue share in 2023. The Global market for Esomeprazole is significantly influenced by North America, where a heightened presence of GERD and peptic ulcers drives demand for medication that suppresses acid production like Esomeprazole. In this region, the healthcare infrastructure is robust and advanced, with skilled medical experts/professionals who take proactive measures to manage acid-related disorders, all contributing factors leading to the continued prominence of Esomeprazole use in North America. Esomeprazole is in high demand within the United States due to a significant number of individuals suffering from GERD and related ailments. Various lifestyle factors commonly found throughout the region, like unhealthy eating habits, obesity, and stress levels, contribute to greater incidences of acid-related disorders. Moreover, Esomeprazole's market share further augments through access to advanced diagnostic resources and widespread encouragement for proactive healthcare practices across the region. The regional market players also engage in various market strategies such as product innovation, product differentiation, mergers, acquisitions, partnerships, and strategic alliances to maintain their competitive edge.

North America Region Esomeprazole Market Share in 2023 - 39.0%

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  • In June 2023: The U.S. Food and Drug Administration (FDA) approved esomeprazole magnesium for delayed-release oral suspension, produced by Zydus Lifesciences Limited, for treating patients with esophagus and stomach disorders. Over the projected time, the esomeprazole market is expected to rise due to this medicinal approval.
Product Type Segment Analysis

The product type segment includes tablets, capsules and others. The capsules segment dominated, with a market share of around 44% in 2023. Capsules occupy a substantial market share within the global market, impacted by patient preferences, prescriber habits, and easy availability. When patients have difficulty swallowing tablets or healthcare providers consider controlled-release capsules more appropriate for certain clinical scenarios, capsules may be preferred. Additional comorbidities or individualized patient considerations can also impact whether one selects capsules over tablets. Certain populations or clinical situations might particularly benefit from capsule formulations. For instance, Esomeprazole's encapsulation allows controlled release to bypass stomach acid and ensure absorption in the small intestine. This is the primary factor for the segment’s growth.

Application Segment Analysis

The application segment is bifurcated into gastroesophageal reflux disease, duodenal ulcers and others. The gastroesophageal reflux disease segment dominated, with a market share of around 53% in 2023. The rising cases of GERD are influencing the segment's growth. This chronic condition causes stomach acid to reflux into the esophagus, resulting in symptoms like regurgitation and heartburn. As a prominent medication for managing GERD due to its strong ability to suppress acid production, Esomeprazole is widely prescribed by medical experts and healthcare professionals. Global incidences of GERD are increasing due to lifestyle adjustments, overweightness and dietary practices. Esomeprazole relieves symptoms by hindering the proton pump in gastric parietal compartments and decreasing acid production. Its dominance holds significant ground within GERD management as a consequence of its extensive prevalence worldwide.

Some of the Key Market Players:
  • Astrazeneca
  • Cadila Pharmaceuticals
  • Sun Pharmaceutical Industries Ltd.
  • Teva Pharmaceutical Industries Ltd.
  • Viatris Inc.
  • Dr. Reddy's Laboratories Ltd.
  • Torrent Pharmaceuticals Ltd.
  • Amneal Pharmaceuticals LLC
  • Glenmark Pharmaceuticals Inc.

Report Description:

Attribute Description
Market Size Revenue (USD Billion)
Market size value in 2023 USD 1.91 Billion
Market size value in 2033 USD 3.22 Billion
CAGR (2024 to 2033) 5.35%
Historical data 2020-2022
Base Year 2023
Forecast 2024-2033
Region The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East & Africa. Furthermore, the regions are further analyzed at the country level.
Segments Application, Product Type

Frequesntly Asked Questions

As per The Brainy Insights, the size of the Esomeprazole market was valued at 1.91 billion in 2023 to USD 3.22 billion by 2033.

The global Esomeprazole market is growing at a CAGR of 5.35% during the forecast period 2024-2033.

North America region became the largest market for Esomeprazole.

The rising incidences of GERD is driving the market's growth.

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This study forecasts revenue at global, regional, and country levels from 2019 to 2032. The Brainy Insights has segmented the global Esomeprazole market based on below-mentioned segments:

Global Esomeprazole Market by Product Type:

  • Tablets
  • Capsules
  • Others

Global Esomeprazole Market by Application:

  • Gastroesophageal Reflux Disease
  • Duodenal Ulcers
  • Others

Global Esomeprazole Market by Region:

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
  • Asia-Pacific
    • Japan
    • China
    • India
  • South America
    • Brazil
  • Middle East and Africa  
    • UAE
    • South Africa


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