Corneal Implants Market

Corneal Implants Market Size By Type (Synthetic and Human Cornea), By Surgery Method (Endothelial Keratoplasty and Penetrating Keratoplasty), By Application (Fuchs Dystrophy, Corneal Ulcers, Keratoconus, Infectious Keratitis, and Others), and By End-User (Ambulatory Surgical Centers, Ophthalmic Centers, and Hospitals), Regions, Global Industry Analysis, Share, Growth, Trends, and Forecast 2024 to 2033

Base Year: 2023 Historical Data: 2020-22
  • Report ID: TBI-14042
  • Published Date: Jan, 2024
  • Pages: 236
  • Category: Healthcare
  • Format: PDF
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The global corneal implants market was valued at USD 439.8 million in 2023, growing at a CAGR of 6.1% from 2024 to 2033. The market is expected to reach USD 795.0 million by 2033. The rising prevalence of corneal diseases drives the growth of the corneal implant market. Additionally, the market is growing due to the rise in corneal blindness in emerging nations and the demand for corneal transplants.

Market Introduction:

A corneal implant, sometimes called a corneal graft, is a surgical process in which a donor cornea is used to replace a damaged cornea. The cornea is the transparent, dome-shaped outer layer of the eye responsible for concentrating light onto the retina, making it vital for vision. Corneal implants are usually advised when the cornea becomes hazy, scarred, or distorted due to keratoconus, Fuchs' dystrophy, corneal damage, or infections. These diseases frequently come with vision impairment, pain, and light sensitivity, all of which call for attention. Corneal transplants come in various forms, targeting different layers of the cornea with partial-thickness (lamellar) and full-thickness (penetrating) transplants. The kind of transplant chosen is influenced by the patient's condition and medical recommendations. In 116 countries, about 185,000 corneal transplants are performed each year. In 82 countries, 284,000 corneas are obtained concurrently. An estimated 12.7 million people are on the waiting list for corneal transplants, with only one in seven requests being fulfilled worldwide.

Corneal Implants Market Size

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Recent Development

In 2022, The affordable, implantable CorNeat KPro artificial cornea will be made by CorNeat Vision. The CorNeat KPro is designed to completely and instantly restore the vision of patients who are corneally blind. It is meant to repair corneas that have been injured, deformed, or opacified.

In 2022, A collaborative licence agreement for corneal endothelial cell regeneration therapy in Greater China was obtained by Celregen and Cellusion Inc.

 In 2022, Precise Bio and Carl Zeiss Meditec partnered to develop and produce tissue-based implants for ophthalmology.

Market Dynamics:

Drivers

Increasing incidence of corneal diseases- The market for corneal implants is expanding substantially due to the rising prevalence of corneal disorders. Various disorders that impact the cornea, the clear front surface of the eye, are called corneal illnesses. Genetic factors, ocular trauma, infections, or degenerative changes can all cause these diseases. Keratoconus, Fuchs' endothelial dystrophy, and corneal injuries from infections or accidents are a few of the frequent corneal illnesses. One important element influencing the increased prevalence of corneal disorders is lifestyle changes. Long-term screen time, exposure to environmental toxins, and increased contact lens wear are common aspects of modern lives that raise the risk of corneal issues. Corneal disorders can also arise as a result of age-related changes and hereditary predisposition.

Restraints:

Regulatory approval- Corneal implants' development and regulatory approval are subject to strict procedures and guidelines. While these rules are necessary to guarantee the effectiveness and safety of medical devices, they also pose difficulties for researchers and producers in the corneal implant sector. Medical devices, such as corneal implants, go through several stages of development, including preclinical testing and clinical trials. These tests are carried out to determine the safety and efficacy of the implant in treating particular eye disorders. To substantiate safety and efficacy claims, regulatory bodies like the European Medicines Agency (EMA) in Europe and the U.S. Food and Drug Administration (FDA) in the United States need copious amounts of data.

Opportunities:

Technological advancements in corneal implants- Technological advancements are expected to propel the growth and development of the corneal implant market. Ultimately aiming to improve patient outcomes and expand the application of this revolutionary medical intervention, these advancements encompass a range of corneal implant research domains, such as composition, production techniques, and architecture. For example, in 2022, medical professionals and polymer scientists from the University of Melbourne collaborated to create a novel, patentable method that might improve outcomes for patients having corneal transplant surgery. Thus, technological advancements in corneal implants are expected to provide growth opportunities for the market during the forecast period.

Regional segmentation analysis:

The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America emerged as the largest global corneal implants market, with a 48.9% market revenue share in 2023.

The market for corneal implants in North America has grown significantly in recent years due to several variables that reflect changing healthcare trends and technological improvements. The need for corneal implants has increased due to the growing incidence of corneal conditions, including keratoconus, dystrophies, and corneal scarring. There is a sizable patient base for corneal implant operations because these disorders can significantly impair vision and necessitate surgical intervention. The ongoing advancements in corneal implant technologies have enhanced the safety and effectiveness of treatments. Advancements like artificial corneas and improved biocompatible materials have improved surgical results and increased patient and physician interest in these implants.

North America Region Corneal Implants Market Share in 2023 - 48.9%

 

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Type Segment Analysis

The type segment is divided into synthetic and human cornea. The human cornea segment dominated the market, with a market share of around 59% in 2023. Some of the reasons contributing to the greatest revenue share of this category are enhanced visual acuity (VA) outcomes and a high success rate of the human cornea, which is believed to be as high as 95% with minimal requirements of recurrent follow-ups.

Surgery Method Segment Analysis

The surgery method segment is divided into endothelial keratoplasty and penetrating keratoplasty. The penetrating keratoplasty segment dominated the market, with a market share of around 54% in 2023. Since penetrating keratoplasty is a recognised safe and effective surgery, it is the standard procedure for corneal transplantation. According to the Eye Bank Association of America, 46% of the cornea produced by the eye bank was utilised for penetrating keratoplasty. Its acceptance rate has gradually decreased recently due to the availability of substitute techniques that yield encouraging outcomes.

Application Segment Analysis

The application segment is divided into fuchs dystrophy, corneal ulcers, keratoconus, infectious keratitis, and others. The fuchs dystrophy segment dominated the market, with a market share of around 28% in 2023. The expansion of this segment is anticipated to be driven by the ageing population, which is more likely to develop fuchs dystrophy. Fuchs dystrophy is a corneal ailment expected to become more common as the world's population ages. This rising incidence emphasises how much more commonplace therapeutic techniques like corneal implants are becoming.

End-User Segment Analysis

The end-user segment is divided into ambulatory surgical centres, ophthalmic centres, and hospitals. The hospital segment dominated the market, with a market share of around 43% in 2023. The factors anticipated to propel the expansion of this segment are the availability of international eye banks, the prevalence of highly skilled surgeons, and the increasing number of patients. The enhanced infrastructure that has led to the rise of the hospital segment is linked to rapid technological advancements.

Some of the Key Market Players:
  • AJL Opthalmic SA
  • KeraMed, Inc
  • CorNeat Vision
  • LinkoCare Life Sciences AB
  • DIOPTEX
  • Aurolab
  • CorneaGen
  • Presbia Plc
  • Mediphacos
  • EyeYon Medical

Report Description:

Attribute Description
Market Size Revenue (USD Million)
Market size value in 2023 USD 439.8 Million
Market size value in 2033 USD 795.0 Million
CAGR (2024 to 2033) 6.1%
Historical data 2020-2022
Base Year 2023
Forecast 2024-2033
Region The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East & Africa. Furthermore, the regions are further analyzed at the country level.
Segments Type, Surgery Method,  Application, End-User

Frequesntly Asked Questions

As per The Brainy Insights, the size of the corneal implants market was valued at USD 439.8 million in 2023 to USD 795.0 million by 2033.

The global corneal implants market is growing at a CAGR of 6.1% during the forecast period 2024-2033.

North America emerged as the largest corneal implants market.

Key players in the corneal implants market are AJL Opthalmic SA, KeraMed, Inc, CorNeat Vision, LinkoCare Life Sciences AB, DIOPTEX, Aurolab, CorneaGen, Presbia Plc, Mediphacos, and EyeYon Medical.

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This study forecasts global, regional, and country revenue from 2020 to 2033. The Brainy Insights has segmented the global corneal implants market based on the below-mentioned segments:

Global Corneal Implants Market By Type:

  • Synthetic
  • Human Cornea

Global Corneal Implants Market By Surgery Method:

  • Endothelial Keratoplasty
  • Penetrating Keratoplasty 

Global Corneal Implants Market By Application:

  • Fuchs Dystrophy
  • Corneal Ulcers
  • Keratoconus
  • Infectious Keratitis
  • Others 

Global Corneal Implants Market By End-User:

  • Ambulatory Surgical Centers
  • Ophthalmic Centers
  • Hospitals 

Global Corneal Implants Market By Region:                               

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
  • Asia-Pacific
    • Japan
    • China
    • India
  • South America
    • Brazil
  • Middle East and Africa  
    • UAE
    • South Africa

Methodology

Research has its special purpose to undertake marketing efficiently. In this competitive scenario, businesses need information across all industry verticals; the information about customer wants, market demand, competition, industry trends, distribution channels etc. This information needs to be updated regularly because businesses operate in a dynamic environment. Our organization, The Brainy Insights incorporates scientific and systematic research procedures in order to get proper market insights and industry analysis for overall business success. The analysis consists of studying the market from a miniscule level wherein we implement statistical tools which helps us in examining the data with accuracy and precision. 

Our research reports feature both; quantitative and qualitative aspects for any market. Qualitative information for any market research process are fundamental because they reveal the customer needs and wants, usage and consumption for any product/service related to a specific industry. This in turn aids the marketers/investors in knowing certain perceptions of the customers. Qualitative research can enlighten about the different product concepts and designs along with unique service offering that in turn, helps define marketing problems and generate opportunities. On the other hand, quantitative research engages with the data collection process through interviews, e-mail interactions, surveys and pilot studies. Quantitative aspects for the market research are useful to validate the hypotheses generated during qualitative research method, explore empirical patterns in the data with the help of statistical tools, and finally make the market estimations.

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Our research methodology encompasses an idyllic combination of primary and secondary initiatives. Key phases involved in this process are listed below:

MARKET RESEARCH PROCESS

Data Procurement:

The phase involves the gathering and collecting of market data and its related information with the help of different sources & research procedures.

The data procurement stage involves in data gathering and collecting through various data sources.

This stage involves in extensive research. These data sources includes:

Purchased Database: Purchased databases play a crucial role in estimating the market sizes irrespective of the domain. Our purchased database includes:

  • The organizational databases such as D&B Hoovers, and Bloomberg that helps us to identify the competitive scenario of the key market players/organizations along with the financial information.
  • Industry/Market databases such as Statista, and Factiva provides market/industry insights and deduce certain formulations. 
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Primary Research: The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. Primary research mainly involves in telephonic interviews, E-mail interactions and face-to-face interviews with the raw material providers, manufacturers/producers, distributors, & independent consultants. The interviews that we conduct provides valuable data on market size and industry growth trends prevailing in the market. Our organization also conducts surveys with the various industry experts in order to gain overall insights of the industry/market. For instance, in healthcare industry we conduct surveys with the pharmacists, doctors, surgeons and nurses in order to gain insights and key information of a medical product/device/equipment which the customers are going to usage. Surveys are conducted in the form of questionnaire designed by our own analyst team. Surveys plays an important role in primary research because surveys helps us to identify the key target audiences of the market. Additionally, surveys helps to identify the key target audience engaged with the market. Our survey team conducts the survey by targeting the key audience, thus gaining insights from them. Based on the perspectives of the customers, this information is utilized to formulate market strategies. Moreover, market surveys helps us to understand the current competitive situation of the industry. To be precise, our survey process typically involve with the 360 analysis of the market. This analytical process begins by identifying the prospective customers for a product or service related to the market/industry to obtain data on how a product/service could fit into customers’ lives.

Secondary Research: The secondary data sources includes information published by the on-profit organizations such as World bank, WHO, company fillings, investor presentations, annual reports, national government documents, statistical databases, blogs, articles, white papers and others. From the annual report, we analyse a company’s revenue to understand the key segment and market share of that organization in a particular region. We analyse the company websites and adopt the product mapping technique which is important for deriving the segment revenue. In the product mapping method, we select and categorize the products offered by the companies catering to domain specific market, deduce the product revenue for each of the companies so as to get overall estimation of the market size. We also source data and analyses trends based on information received from supply side and demand side intermediaries in the value chain. The supply side denotes the data gathered from supplier, distributor, wholesaler and the demand side illustrates the data gathered from the end customers for respective market domain.

The supply side for a domain specific market is analysed by:

  • Estimating and projecting penetration rates through analysing product attributes, availability of internal and external substitutes, followed by pricing analysis of the product.
  • Experiential assessment of year-on-year sales of the product by conducting interviews.

The demand side for the market is estimated through:

  • Evaluating the penetration level and usage rates of the product.
  • Referring to the historical data to determine the growth rate and evaluate the industry trends

In-house Library: Apart from these third-party sources, we have our in-house library of qualitative and quantitative information. Our in-house database includes market data for various industry and domains. These data are updated on regular basis as per the changing market scenario. Our library includes, historic databases, internal audit reports and archives.

Sometimes there are instances where there is no metadata or raw data available for any domain specific market. For those cases, we use our expertise to forecast and estimate the market size in order to generate comprehensive data sets. Our analyst team adopt a robust research technique in order to produce the estimates:

  • Applying demographic along with psychographic segmentation for market evaluation
  • Determining the Micro and Macro-economic indicators for each region 
  • Examining the industry indicators prevailing in the market. 

Data Synthesis: This stage involves the analysis & mapping of all the information obtained from the previous step. It also involves in scrutinizing the data for any discrepancy observed while data gathering related to the market. The data is collected with consideration to the heterogeneity of sources. Robust scientific techniques are in place for synthesizing disparate data sets and provide the essential contextual information that can orient market strategies. The Brainy Insights has extensive experience in data synthesis where the data passes through various stages:

  • Data Screening: Data screening is the process of scrutinising data/information collected from primary research for errors and amending those collected data before data integration method. The screening involves in examining raw data, identifying errors and dealing with missing data. The purpose of the data screening is to ensure data is correctly entered or not. The Brainy Insights employs objective and systematic data screening grades involving repeated cycles of quality checks, screening and suspect analysis.
  • Data Integration: Integrating multiple data streams is necessary to produce research studies that provide in-depth picture to the clients. These data streams come from multiple research studies and our in house database. After screening of the data, our analysts conduct creative integration of data sets, optimizing connections between integrated surveys and syndicated data sources. There are mainly 2 research approaches that we follow in order to integrate our data; top down approach and bottom up approach.

Market Deduction & Formulation: The final stage comprises of assigning data points at appropriate market spaces so as to deduce feasible conclusions. Analyst perspective & subject matter expert based holistic form of market sizing coupled with industry analysis also plays a crucial role in this stage.

This stage involves in finalization of the market size and numbers that we have collected from data integration step. With data interpolation, it is made sure that there is no gap in the market data. Successful trend analysis is done by our analysts using extrapolation techniques, which provide the best possible forecasts for the market.

Data Validation & Market Feedback: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helps us finalize data-points to be used for final calculations.

The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. The data validation interview and discussion panels are typically composed of the most experienced industry members. The participants include, however, are not limited to:

  • CXOs and VPs of leading companies’ specific to sector
  • Purchasing managers, technical personnel, end-users
  • Key opinion leaders such as investment bankers, and industry consultants

Moreover, we always validate our data and findings through primary respondents from all the major regions we are working on.

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