Biobetters Market

Biobetters Market Size by Molecule Type (Monoclonal Antibodies (mAbs) Biobetters, Insulin Biobetters, Erythropoietin Biobetters, Granulocyte Colony Stimulating Factor (G-CSF) Biobetters, Interferon Biobetters and Others), Disease Indication (Cancer, Autoimmune Disorders, Diabetes, Hematological Disorders, Infectious Diseases, Hormonal Disorders and Others), Route of Administration (Intravenous (IV, Subcutaneous (SC) and Others), End User (Hospitals, Specialty Clinics, Homecare Settings and Research & Academic Institutes), Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies and Specialty Clinics), Regions, Global Industry Analysis, Share, Growth, Trends, and Forecast 2025 to 2034

Base Year: 2024 Historical Data: 2021-23
  • Report ID: TBI-14798
  • Published Date: Aug, 2025
  • Pages: 238
  • Category: Healthcare
  • Format: PDF
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Market Introduction

The global Biobetters market was valued at USD 68.53 billion in 2024 and growing at a CAGR of 8.60% from 2025 to 2034. The market is expected to reach USD 156.38 billion by 2034. With the help of biobetters, the overall cost of healthcare can be reduced through their use. This is possible because, although the cost of biobetters is high, their effectiveness enables significant improvements in patient health, resulting in fewer and less frequent doctor visits. Apart from this, due to increased public and private investments, the research and development of biobetters can be accelerated, allowing for the launch of new biobetters medicines in the market in the coming years. These medicines can be used to treat a wide range of diseases, not just chronic ones. Biobetters are superior versions of existing biologic drugs. These enhanced versions work more safely and efficiently than before. The primary reason for this is the chemical and molecular modifications made in biobetters, which confer superior properties to the original drugs. Biobetters also reduce the side effects of the original medicines. This makes it easier to treat patients and improves their health faster. Many biobetters are redesigned to reduce the risk of immune reactions and increase the safety of biologics. Biobetters have a longer shelf life and require less refrigeration, making their distribution easier to handle. Apart from this, due to the changes made in their formulations, these biobetters are easy to handle and store. Due to the production of biobetters, it has become easy for pharma companies to survive in the market. This is because structural and functional changes are made during the development of biobetters, which prevents the patents of old medicines from expiring, allowing companies to remain in the market.

Biobetters Market Size

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Market Dynamics

Drivers

Rising Demand for Improved Biologics - Many biologics have a short shelf life, which limits their ability to function at full efficiency. Biobetters are designed to overcome this problem, allowing patients to access the right treatment easily. Apart from this, as technology advances, more priority is being given to patient safety. Preferences such as administering the patient in limited doses and simultaneously eliminating the risk of immune reactions are being considered. Due to this, the importance of biobetters increases because they are adept in all these areas, which is why their adoption rate is increasing. Due to the growing trend of personalised medicine, the need for biobetters is increasing because biobetters improve target specificity and reduce off-target effects.

Restraints

High Development Costs and Time - The development cost of biobetters is very high, which means many patients are unable to afford them. The cost of biobetters is high because they are created by redesigning existing medicines, and a significant amount of money and time is invested in the research and development of this redesign. Apart from this, these biobetters also have to pass regulatory checks because they are also treated like new biologic products. A significant amount of investment is made in the manufacturing of biobetters, which is only affordable for large companies. Due to this, competition in this market is limited, and the speed of innovation is also slow. Apart from this, even if the clinical trials fail, the manufacturers of these biobetters suffer financial loss because they have to repeat the entire process.

Opportunities

Expanding Use in Chronic and Lifestyle Diseases- The market for biobetters is expected to grow in the coming years due to the increasing prevalence of chronic diseases. This is because chronic diseases such as cancer and type 2 diabetes, along with many other diseases, require long-term care and treatment, and biobetters are well integrated with these treatments. Their cost is high due to their redesigned structure, but their effectiveness increases as a result, allowing patients to avoid frequent physician visits. In developing countries such as China and India, the cases of chronic diseases are increasing, resulting in a high demand for biobetters in these sectors in the coming years, which can lead to increased market growth.

Challenges

Strong Market Competition from Biosimilars - The cost of biosimilars is significantly lower than that of biologics, which could lead to an increase in their use. Biosimilars are made by improving existing biologics and replicating them at a lower cost. This cost variation has led to biosimilars not being used in many cost-sensitive areas. Both physicians and patients prefer biosimilars because they have high market credibility and have been used for a long time, which allows their efficacy to be readily apparent. While awareness about biologics is low, there is a need for evidence and clinical education to support them. Due to the lack of supporting data, the market share of biobetters is relatively low compared to biosimilars, and their adoption rate is also low.

Segment Analysis

Regional segmentation analysis

The regions analyzed for the market include North America, Europe, South America, Asia Pacific, the Middle East, and Africa. North America emerged as the largest market for the global Biobetters market, with a 45.24% share of the market revenue in 2024.

The North American region holds a strong position in the biobetters market due to its robust and well-established healthcare infrastructure. Apart from this, a significant amount of investment is made in healthcare in this region, enabling the improvement of existing technologies and the development of new ones. The biobetters developed in North America have high efficiency, and their lifespan is also long, making them easy to use. Due to high healthcare expenditures, companies in this region receive support to develop new products, enabling the creation of new treatments and facilitating the cure of patients. Patients and physicians in this region are more aware of biobetters, which makes their adoption easier.

North America Region Biobetters Market Share in 2024 - 45.24%

 

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Molecule Type Segment Analysis

The molecule type segment is divided into monoclonal antibodies (mAbs) biobetters, insulin biobetters, erythropoietin biobetters, granulocyte colony stimulating factor (G-CSF) biobetters, interferon biobetters and others. The monoclonal antibodies (mAbs) biobetters segment dominated the market, with a market share of 30.25% in 2024. Monoclonal Antibodies (mAbs) Biobetters are used to treat various diseases, including lung cancer, breast cancer, COVID-19, and HIV. This has increased the commercial demand for biobetters. These biobetters are mostly used in life-threatening and high-impact conditions, which makes it easy to justify their high price. Apart from this, the innovation potential of these mAbs biobetters is very high,  which makes it easy to create their superior versions with enhanced safety.

Disease Indication Segment Analysis

The disease indication segment is divided into cancer, autoimmune disorders, diabetes, hematological disorders, infectious diseases, hormonal disorders and others. The cancer segment dominated the market, with a market share of 28.57% in 2024. Biobetters are used a lot for the treatment of cancer. Biobetters are showing high efficiency and positive results. Many people around the world have lost their lives due to cancer because of not getting the right treatment, due to which biobetters are being innovated and prepared for the treatment of cancer. Apart from this, cancer therapy has many side effects, due to which patients leave the treatment incomplete. Still, biobetters have been designed in such a way that their side effects are minimized, allowing patients to continue the treatment.

Route of Administration Segment Analysis

The route of administration segment is divided into intravenous (IV, subcutaneous (SC) and others. The subcutaneous (SC) segment dominated the market, with a market share of 42.24% in 2024. Subcutaneous (SC) delivery is an effective method and is superior to other delivery methods. The subcutaneous delivery method enables patients to receive medications at home, thereby reducing the burden of hospital visits on both the patient and the healthcare system. Additionally, subcutaneous (SC) delivery ensures patient safety and treatment efficacy. Adoption of this method enables the use of more resources, making healthcare systems more cost-effective.

End User Segment Analysis

The end user segment is divided into hospitals, specialty clinics, homecare settings and research & academic institutes. The hospitals segment dominated the market, with a market share of 45.68% in 2024. Skilled expertise is required for the administration of biobetters, which can only be done in a hospital setting. Because the patient is monitored before and after giving the medicine. Apart from this, in the event of an emergency, the hospital staff is also present, allowing for timely treatment and potentially saving the patient. Hospitals provide a centralized system where treatment for many diseases can be easily found.

Distribution Channel Segment Analysis

The distribution channel segment is divided into hospital pharmacies, retail pharmacies, online pharmacies and specialty clinics. The hospital pharmacies segment dominated the market, with a market share of 35.54% in 2024. Hospital pharmacies have a high market share due to the complex nature of biobetters and their clinical requirements. Biobetters are primarily used in complex conditions where hospital-based protocols must be followed during anti-inflammatory treatment; therefore, it is best to purchase biobetters from hospital pharmacies at such times. Apart from this, due to the short half-lives of biobetters, they are stored in cold storage, making the cold chain services of hospital pharmacies more effective than those of other distribution channels.

Some of the Key Market Players

  • AstraZeneca PLC
  • Amgen
  • F. Hoffmann-La Roche AG
  • Celltrion Inc.
  • Eli Lilly And Company
  • Novo Nordisk A/S
  • AbbVie Inc.
  • Porton Biopharma Limited
  • SERVIER
  • CSL Behring GmbH

Report Description

Attribute Description
Market Size Revenue (USD Billion)
Market size value in 2024 USD 68.53 Billion
Market size value in 2034 USD 156.38 Billion
CAGR (2025 to 2034) 8.60%
Historical data 2021-2023
Base Year 2024
Forecast 2025-2034
Region The regions analyzed for the market are Asia Pacific, Europe, South America, North America, and Middle East & Africa. Furthermore, the regions are further analyzed at the country level.
Segments Molecule Type, Disease Indication, Route of Administration, End User and Distribution Channel

Frequently Asked Questions

As per The Brainy Insights, the size of the biobetters market was valued at USD 68.53 billion in 2024 to USD 156.38 billion by 2034.

The global biobetters market is growing at a CAGR of 8.60% during the forecast period 2025-2034.

The North America region emerged as the largest market for the biobetters.

The rising demand for improved biologics will influence the market's growth.

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This study forecasts revenue at global, regional, and country levels from 2021 to 2034. The Brainy Insights has segmented the global biobetters market based on below-mentioned segments:

Global Biobetters Market by Molecule Type:

  • Monoclonal Antibodies (mAbs) Biobetters
  • Insulin Biobetters
  • Erythropoietin Biobetters
  • Granulocyte Colony Stimulating Factor (G-CSF) Biobetters
  • Interferon Biobetters
  • Others

Global Biobetters Market by Disease Indication:

  • Cancer
  • Autoimmune Disorders
  • Diabetes
  • Hematological Disorders
  • Infectious Diseases
  • Hormonal Disorders
  • Others

Global Biobetters Market by Route of Administration:

  • Intravenous (IV)
  • Subcutaneous (SC)
  • Others

Global Biobetters Market by End User:

  • Hospitals
  • Specialty Clinics
  • Homecare Settings
  • Research & Academic Institutes

Global Biobetters Market by Distribution Channel:

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
  • Specialty Clinics

Global Biobetters Market by Region:

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • U.K.
    • Italy
    • Spain
  • Asia-Pacific
    • Japan
    • China
    • India
  • South America
    • Brazil
  • Middle East and Africa  
    • UAE
    • South Africa

Methodology

Research has its special purpose to undertake marketing efficiently. In this competitive scenario, businesses need information across all industry verticals; the information about customer wants, market demand, competition, industry trends, distribution channels etc. This information needs to be updated regularly because businesses operate in a dynamic environment. Our organization, The Brainy Insights incorporates scientific and systematic research procedures in order to get proper market insights and industry analysis for overall business success. The analysis consists of studying the market from a miniscule level wherein we implement statistical tools which helps us in examining the data with accuracy and precision. 

Our research reports feature both; quantitative and qualitative aspects for any market. Qualitative information for any market research process are fundamental because they reveal the customer needs and wants, usage and consumption for any product/service related to a specific industry. This in turn aids the marketers/investors in knowing certain perceptions of the customers. Qualitative research can enlighten about the different product concepts and designs along with unique service offering that in turn, helps define marketing problems and generate opportunities. On the other hand, quantitative research engages with the data collection process through interviews, e-mail interactions, surveys and pilot studies. Quantitative aspects for the market research are useful to validate the hypotheses generated during qualitative research method, explore empirical patterns in the data with the help of statistical tools, and finally make the market estimations.

The Brainy Insights offers comprehensive research and analysis, based on a wide assortment of factual insights gained through interviews with CXOs and global experts and secondary data from reliable sources. Our analysts and industry specialist assume vital roles in building up statistical tools and analysis models, which are used to analyse the data and arrive at accurate insights with exceedingly informative research discoveries. The data provided by our organization have proven precious to a diverse range of companies, facilitating them to address issues such as determining which products/services are the most appealing, whether or not customers use the product in the manner anticipated, the purchasing intentions of the market and many others.

Our research methodology encompasses an idyllic combination of primary and secondary initiatives. Key phases involved in this process are listed below:

MARKET RESEARCH PROCESS

Data Procurement:

The phase involves the gathering and collecting of market data and its related information with the help of different sources & research procedures.

The data procurement stage involves in data gathering and collecting through various data sources.

This stage involves in extensive research. These data sources includes:

Purchased Database: Purchased databases play a crucial role in estimating the market sizes irrespective of the domain. Our purchased database includes:

  • The organizational databases such as D&B Hoovers, and Bloomberg that helps us to identify the competitive scenario of the key market players/organizations along with the financial information.
  • Industry/Market databases such as Statista, and Factiva provides market/industry insights and deduce certain formulations. 
  • We also have contractual agreements with various reputed data providers and third party vendors who provide information which are not limited to:
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    • Usage rates of a particular product/service on certain demographics mainly focusing on the unmet prerequisites

Primary Research: The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. Primary research mainly involves in telephonic interviews, E-mail interactions and face-to-face interviews with the raw material providers, manufacturers/producers, distributors, & independent consultants. The interviews that we conduct provides valuable data on market size and industry growth trends prevailing in the market. Our organization also conducts surveys with the various industry experts in order to gain overall insights of the industry/market. For instance, in healthcare industry we conduct surveys with the pharmacists, doctors, surgeons and nurses in order to gain insights and key information of a medical product/device/equipment which the customers are going to usage. Surveys are conducted in the form of questionnaire designed by our own analyst team. Surveys plays an important role in primary research because surveys helps us to identify the key target audiences of the market. Additionally, surveys helps to identify the key target audience engaged with the market. Our survey team conducts the survey by targeting the key audience, thus gaining insights from them. Based on the perspectives of the customers, this information is utilized to formulate market strategies. Moreover, market surveys helps us to understand the current competitive situation of the industry. To be precise, our survey process typically involve with the 360 analysis of the market. This analytical process begins by identifying the prospective customers for a product or service related to the market/industry to obtain data on how a product/service could fit into customers’ lives.

Secondary Research: The secondary data sources includes information published by the on-profit organizations such as World bank, WHO, company fillings, investor presentations, annual reports, national government documents, statistical databases, blogs, articles, white papers and others. From the annual report, we analyse a company’s revenue to understand the key segment and market share of that organization in a particular region. We analyse the company websites and adopt the product mapping technique which is important for deriving the segment revenue. In the product mapping method, we select and categorize the products offered by the companies catering to domain specific market, deduce the product revenue for each of the companies so as to get overall estimation of the market size. We also source data and analyses trends based on information received from supply side and demand side intermediaries in the value chain. The supply side denotes the data gathered from supplier, distributor, wholesaler and the demand side illustrates the data gathered from the end customers for respective market domain.

The supply side for a domain specific market is analysed by:

  • Estimating and projecting penetration rates through analysing product attributes, availability of internal and external substitutes, followed by pricing analysis of the product.
  • Experiential assessment of year-on-year sales of the product by conducting interviews.

The demand side for the market is estimated through:

  • Evaluating the penetration level and usage rates of the product.
  • Referring to the historical data to determine the growth rate and evaluate the industry trends

In-house Library: Apart from these third-party sources, we have our in-house library of qualitative and quantitative information. Our in-house database includes market data for various industry and domains. These data are updated on regular basis as per the changing market scenario. Our library includes, historic databases, internal audit reports and archives.

Sometimes there are instances where there is no metadata or raw data available for any domain specific market. For those cases, we use our expertise to forecast and estimate the market size in order to generate comprehensive data sets. Our analyst team adopt a robust research technique in order to produce the estimates:

  • Applying demographic along with psychographic segmentation for market evaluation
  • Determining the Micro and Macro-economic indicators for each region 
  • Examining the industry indicators prevailing in the market. 

Data Synthesis: This stage involves the analysis & mapping of all the information obtained from the previous step. It also involves in scrutinizing the data for any discrepancy observed while data gathering related to the market. The data is collected with consideration to the heterogeneity of sources. Robust scientific techniques are in place for synthesizing disparate data sets and provide the essential contextual information that can orient market strategies. The Brainy Insights has extensive experience in data synthesis where the data passes through various stages:

  • Data Screening: Data screening is the process of scrutinising data/information collected from primary research for errors and amending those collected data before data integration method. The screening involves in examining raw data, identifying errors and dealing with missing data. The purpose of the data screening is to ensure data is correctly entered or not. The Brainy Insights employs objective and systematic data screening grades involving repeated cycles of quality checks, screening and suspect analysis.
  • Data Integration: Integrating multiple data streams is necessary to produce research studies that provide in-depth picture to the clients. These data streams come from multiple research studies and our in house database. After screening of the data, our analysts conduct creative integration of data sets, optimizing connections between integrated surveys and syndicated data sources. There are mainly 2 research approaches that we follow in order to integrate our data; top down approach and bottom up approach.

Market Deduction & Formulation: The final stage comprises of assigning data points at appropriate market spaces so as to deduce feasible conclusions. Analyst perspective & subject matter expert based holistic form of market sizing coupled with industry analysis also plays a crucial role in this stage.

This stage involves in finalization of the market size and numbers that we have collected from data integration step. With data interpolation, it is made sure that there is no gap in the market data. Successful trend analysis is done by our analysts using extrapolation techniques, which provide the best possible forecasts for the market.

Data Validation & Market Feedback: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helps us finalize data-points to be used for final calculations.

The Brainy Insights interacts with leading companies and experts of the concerned domain to develop the analyst team’s market understanding and expertise. It improves and substantiates every single data presented in the market reports. The data validation interview and discussion panels are typically composed of the most experienced industry members. The participants include, however, are not limited to:

  • CXOs and VPs of leading companies’ specific to sector
  • Purchasing managers, technical personnel, end-users
  • Key opinion leaders such as investment bankers, and industry consultants

Moreover, we always validate our data and findings through primary respondents from all the major regions we are working on.

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